精密な分析物測定のための敏感な正確な抗ストレプトリシンO反応体ASOテストキット

Product Description:

The Anti-Streptolysin O (ASO) Reagent is an in vitro diagnostic tool designed for the qualitative or quantitative determination of Anti-Streptolysin O antibodies in human serum or plasma. These antibodies are produced by the immune system in response to an infection caused by Group A Streptococcus bacteria, specifically targeting the streptolysin O toxin secreted by these pathogens.

1. Intended Use:

   • The ASO Reagent is used to detect and measure ASO antibodies, aiding in the diagnosis of recent or ongoing streptococcal infections, such as strep throat, scarlet fever, or rheumatic fever.

   • It is commonly employed in clinical laboratories to support the diagnosis of post-streptococcal complications, including rheumatic heart disease or glomerulonephritis.

2. Principle of the Test:

   • The reagent typically utilizes an immunoturbidimetric or latex agglutination method.

   • In the presence of ASO antibodies, the reagent (containing streptolysin O antigen) forms antigen-antibody complexes, which can be measured spectrophotometrically or visually observed for agglutination.

3. Components:

   • Streptolysin O antigen: The key component that binds to ASO antibodies in the sample.

   • Buffer solution: Maintains optimal pH and ionic strength for the reaction.

   • Control samples: Positive and negative controls to validate the test results.

   • Latex particles (if applicable): Coated with streptolysin O antigen for agglutination-based tests.

4. Storage and Stability:

   • The reagent should be stored at 2-8°C (refrigerated) to maintain stability.

   • Avoid freezing or exposure to direct sunlight.

5. Performance:

   • High sensitivity and specificity for detecting ASO antibodies.

   • Results are typically available within minutes to hours, depending on the method used.

6. Clinical Significance:

   • Elevated ASO titers indicate a recent or past streptococcal infection.

   • Serial testing may be performed to monitor antibody levels and assess the progression or resolution of the infection.

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